Has a BMI greater than 31

Has had any relevant injury at the sensor location site

Has deformities or abnormalities that may prevent proper application of the device under test

Has a known respiratory condition

Is currently a smoker

Has a known heart or cardiovascular condition

Is currently pregnant

Is female and actively trying to get pregnant

Has a clotting disorder

Is known to have a hemoglobinopathy such as (anemia, bilirubinemia, sickle-cell anemia, inherited or congenital methemoglobinemia)

The subject has a COHb greater than 3% or MetHb greater than 2%

Has taken blood thinners or medication with aspirin within the last 24 hours

Has unacceptable collateral circulation from the ulnar artery

Has donated more than 300 mL of blood within one month prior to start of study

Is unwilling or unable to provide written informed consent to participate in the study

Is unwilling or unable to comply with the study procedures

Has another health condition which in the opinion of the principal investigator makes him/her unsuitable for testing

Dysfunctional Hemoglobin