Finding studies
Finding studies
Take this into the appointment.
Saves the questions and what to expect into your notes, next to the visit they belong to.
Lead
NRG Oncology
With
PRIMARY OBJECTIVES: -To select the arm(s) achieving a 2-year progression-free survival rate of \>= 85% without unacceptable swallowing toxicity at 1 year. SECONDARY OBJECTIVES: * To determine patterns of failure (locoregional relapse versus distant) and survival -(overall and progression-free) at 6 months and 2 years. * To determine acute toxicity profiles at the end of radiation therapy and at 1 and 6 months. * To determine late toxicity profiles at 1 and 2 years. * To determine patient-reported swallowing outcomes at 6 months and 1 and 2 years. * To determine the predictive value of 12-14 week, post-treatment fludeoxyglucose F 18 (FDG)-positron emission tomography (PET)/computed tomography (CT) for locoregional control and progression free survival (PFS) at 2 years. * To determine the predictive value of blood and tissue biomarkers for disease outcomes at 2 years. * To determine swallowing recovery per videofluoroscopy imaging at 2 years. After completion of study treatment, patients are followed at 1 and 3 months then every 3 months for 2 years, every 6 months for 3 years, and then annually thereafter.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
