Lead Sponsor

Mayo Clinic

Age

18 - 30 years

Sex

ALL

Healthy Volunteers

Yes

•Male and female subjects between 18-30 years of age
•Diagnosis of ADPKD
•Glomerular Filtration Rate (GFR) of \> or = to 60 mL/min (Chronic Kidney Disease-Epidemiology Collaboration equation)
•Ability to provide written, informed consent
•Male and female subjects between 18-30 years of age
•Glomerular Filtration Rate (GFR) of \> or = to 60 mL/min (Chronic Kidney Disease-Epidemiology Collaboration equation)
•Ability to provide written, informed consent

•Clinically significant concomitant systemic disease
•Subjects with Diabetes Mellitus
•Urinary protein excretion
•Abnormal urinalysis suggestive of concomitant glomerular disease
•Subjects having contraindications to, or interference with MRI assessments
•Subjects with supine blood pressure higher than 140/90 mm Hg or taking blood pressure medications
•Previous personal or family history of kidney disease
•Clinically significant concomitant systemic disease
•Subjects with Diabetes Mellitus
•Urinary protein excretion
•Abnormal urinalysis suggestive of concomitant glomerular disease
•Subjects having contraindications to, or interference with MRI assessments
•Subjects with supine blood pressure higher than 140/90 mm Hg or taking blood pressure medications