Imaging Techniques in CT: Technical Development

Exclusion Criteria

• •Prior CT scan in the last 12 months for new volunteers or healthy volunteers enrolled in NIH trials OR Prior CT scan in the last 6 months for patients enrolled in a treatment or interventional trial
• •Pregnant women
• •Over 500 lbs and/or a body circumference that prevents the study subject from lying flat in the scanner
• •Claustrophobia requiring sedation or anesthesia.
• •Known or suspected genetic predisposition to cancer
• •Any contraindications that the research team identifies from the subject, radiology department CT and/or MRI questionnaires, and/or History and Assessment.
• •Exclusion for participation for iodinated contrast for CT
• •Allergy to iodinated contrast for scans (study subject will be eligible for non-contrast scans)
• •Acute renal failure, renal transplant, dialysis and renal failure (clinically diagnosed).\<TAB\>
• •Lactating women
• •Patient preference to not undergo intravenous line placement and/or receive iodinated contrast. Contrast administration is optional and participants may still undergo a non-contrast study.
• •Use of metformin-containing products less than 24 hours prior To CT contrast administration
• •Other contraindications to iodinated contrast media as determined by the research team.
• •Exclusion for participation for Gadolinium contrast for MRI
• •Allergy to gadolinium for scans using contrast; will be eligible for non-contrast scans.
• •Acute renal failure, renal transplant, dialysis and renal failure individuals ( Lab Eligibility parameters and/or clinically diagnosed).\<TAB\>
• •Lactating women
• •Patient preference to not undergo intravenous line placement and/or receive gadolinium contrast. Contrast administration is optional and participants may still undergo a non-contrast study.
• •Other contraindications to gadolinium contrast media as determined by the research team.