Lead Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Collaborators

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Parkinson's disease as perMDS criteria
•Evidence of cognitive dysfunction (clinical impression of mild cognitive impairment and MOCA \<=27)
•Presence of OSA (apnea-hypopnea index RDI ≥ 15/h) on screening diagnostic polysomnography (PSG)
•Stable regimen of anti-PD medication for 1 month prior
•Adequate knowledge of English or French for completion of study assessment.

•Oxygen saturation \<75% for \>10% of the diagnostic polysomnography as this should lead to active PAP treatment
•Other major neurological disorder
•Unstable cardiac disease, uncontrolled hypertension, or diabetes
•Active cancer or other disorder with an expected survival \< 6 months
•Active treatment of OSA (prior diagnosis of OSA will constitute an exclusion criterion only if the patient is currently being treated for the OSA)
•Significant vision or hearing impairment that could affect performance on neurocognitive assessment tasks.
•Latex allergy.