Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes

Inclusion Criteria

• •Informed consent provided
• •Age \> or = to 18 years of age
• •Patient group FAP
• •\- Clinical diagnosis of familial adenomatous polyposis
• •Patient group Lynch syndrome Clinical diagnosis of Lynch syndrome
• •Patient group MAP
• •\- Clinical diagnosis of MYH-associated polyposis and presence of more than 20 colon polyps
• •Control group (FAP)
• •\- Genetically related family member of patient
• •Patients: Able and willing to attend routine follow-up as advised
• •Controls, i.e. relatives of patients: Willingness to give blood at each routine follow-up as advised for the diseased relative