Safety and Efficacy of an Anticholinergic Agent for Treatment of Primary Axillary Hyperhidrosis

Inclusion Criteria

• •Healthy volunteers with primary axillary hyperhidrosis
• •Poor quality of life rating on the Hyperhidrosis Disease Severity Scale (score of 3 or 4)
• •Has a baseline gravimetric measurement of spontaneous resting sweat production of ≥100 mg/10 min at room at room temperature in at least one axilla
• •Meets at least two of the following criteria (self-reported):
• •* sweating is bilateral and symmetrical
• •* excessive sweating impairs daily activities
• •* subject experiences at least one sweating episode per week
• •* excessive sweating onset was earlier than age 25 years
• •* has a positive family history for excessive sweating
• •* cessation of sweating during sleep