Use of 6% Hydroxyethylstarch (130/0.4) in Cardiac Surgical Patients

Exclusion Criteria

• •Patients with renal failure with oliguria or anuria not related to hypovolemia.
• •Patients receiving dialysis.
• •Patients with preoperative renal insufficiency (Creatinine \> 1.6 mg/dL)
• •Anticipated deep hypothermic circulatory arrest
• •Known hypersensitivity or allergy to hydroxyethyl starch or the excipients of hydroxyethyl starch
• •Clinical conditions with volume overload (e.g., patients in pulmonary edema or congestive heart failure)
• •Patients with severe hypernatremia or severe hyperchloremia
• •Patients with intracranial bleeding
• •Pregnant or breast feeding women
• •Critically ill adult patients, including patients with sepsis, due to increased risk of mortality and renal replacement therapy, (e.g. patients who are hospitalized in the intensive care unit prior to surgery)
• •Severe liver disease
• •Pre-existing coagulation or bleeding disorders
• •Any contraindications to proposed interventions.