Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Allergan
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
History of chronic migraine
More than 15 headache days in a 28 day period (headaches that last more than 4 hours and/or require treatment with prescription medication).
You may not be if
Taking opioid-containing products for acute headache treatment more than 8 days during a 28-day period
Previous treatment with botulinum toxin of any serotype for any reason
Previous treatment with topiramate
On a ketogenic diet (high in fat, low in carbohydrates)
History of acute myopia or increased intraocular pressure
Diagnosis of myasthenia gravis, Eaton-Lambert syndrome, amyotrophic lateral sclerosis or any other significant disease that might interfere with neuromuscular function
Acupuncture, transcutaneous electrical stimulation (TENS), cranial traction, dental splints for headache, or injection of anesthetics/steroids in the 4 weeks prior to screening.
Clareo Health | Efficacy and Safety Study of BOTOX® Compared to Topiramate for the Prevention of Chronic Migraine in Adults