An Efficacy And Safety Study Evaluating Tofacitinib With And Without Methotrexate Compared To Adalimumab With Methotrexate

Exclusion Criteria

• •Subjects who have been previously treated with adalimumab or Tofacitinib
• •Subjects with any current malignancy or a history of malignancy, with the exception of adequately treated or excised non metastatic basal cell or squamous cell cancer of the skin or cervical carcinoma in situ.
• •Subjects with specific laboratory test abnormalities
• •Subjects with specific types of infections