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Precision Medicine for Preterm Birth | Clinical Trials | Clareo Health

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COMPLETEDNCT02173210

Precision Medicine for Preterm Birth

This project is examining genetic and metabolic markers for the use of 17 hydroxyprogesterone caproate (17OHPC) in pregnant women with a history of preterm birth (PTB). 17OHPC has been associated with...

Lead sponsor: University of Pennsylvania•2 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University of Pennsylvania

Women with a prior preterm birth will be recruited between 16 and 22 weeks gestation. At this initial time point, samples of cervical epithelial cells and cervicovaginal fluid will be collected. Approximately 8 weeks later, those samples will be collected a second time, along with a blood sample. Outcome data will be collected after delivery.

Age

All ages

Sex

FEMALE

Healthy Volunteers

No

Inclusion Criteria

•Women with a prior spontaneous preterm birth of a singleton pregnancy (delivered at 16-36 6/7 weeks gestation)
•Singleton in the current pregnancy
•Eligible to use 17 hydroxyprogesterone caproate (17OHPC) in this pregnancy for clinical indications
•16-22 weeks gestation at the time of visit 1 assessments

Exclusion Criteria

•Major fetal anomaly
•Allergy to 17OHPC

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 2, 2018Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment380

Start dateJun 2014

Last updatedMay 2, 2018

Condition

Premature Birth

Locations shown

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania

Pennsylvania Hospital

Philadelphia, Pennsylvania

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 2, 2018Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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