Clinical Application of Dual Sentinel Lymph Node Staining Method in Breast Cancer

* 5 patients who receive neoadjuvant chemotherapy with cN1-cN2 or cT2 on TNM staging * sentinel lymph node biopsy(SLNB) by sentinel lymph node staining method using mixture of indocyanine green (ICG) with radioisotope (RI). * indocyanine green (ICG) penetrates human tissue to depths of several millimeters to 2cm, and the fluorescence can be detected percutaneously in real time. * using RI only has several disadvantages such as invisibility,interference. RI only detect sound or confirm numerical value through gamma probe. * ICG can be visualized with a fluorescence imaging system * confirm Identification rate of sentinal lymph node biopsy, and duration of sentinel lymph node biopsy