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The Drug Induced Renal Injury Consortium | Clinical Trials | Clareo Health

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COMPLETEDNCT02159209

The Drug Induced Renal Injury Consortium

Some medications are known to cause kidney damage because the person is allergic to the medication while others cause direct damage to the kidney because they are toxic at certain concentrations. Risk...

Lead sponsor: Ravindra Mehta•8 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Ravindra Mehta

Collaborators

International Serious Adverse Event Consortium

Age

2 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Patients age 2 years and older
•Exposure to a candidate drug for at least 24 hours (see above)
•Patients who have developed DIRI as defined by the primary criteria
•Written informed consent or assent and consent obtained
•If patient lacks capacity to consent then surrogate consent will be obtained

Exclusion Criteria

•Patients with a history of or have a kidney transplant
•Patients with a history of or have a bone marrow transplant
•Patients with Chronic Kidney Disease stage 5 (eGFR \< 15 mL/min/1.73m2)
•Patients on 3 or more causal drugs
•Patients with no history or time course on drug exposure
•Patient who, in the opinion of the Investigator, is not suitable to participate in the study.
•Unable to obtain written informed consent or assent
•Unable to obtain surrogate consent for patients who lack capacity

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 21, 2016Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment634

Start dateFeb 2013

Last updatedApr 21, 2016

Condition

Acute Kidney Injury Adverse Drug Reaction Acute Kidney Failure Kidney Failure Kidney Disease

Locations shown

University of Alabama, Birmingham

Birmingham, Alabama

University of California, San Diego

San Diego, California

Rady Children's Hospital

San Diego, California

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 21, 2016Data synced to Clareo: May 3, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions