Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Nathan Kline Institute for Psychiatric Research
We will enroll 8 subjects in an open label, three session pilot in patients will receive three sessions of tone matching SBR.
5 Subjects will receive D-serine (60mg/kg) taken 1x each week during the SBR sessions. Subjects will receive study drug 30 minutes prior to session.
3 subjects received no intervention
Age
18–64
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
18 to 64 years old,
IQ≥85 and
estimated Glomerular Filtration Rate (GFR) ≥60. All oral and depot antipsychotics (with the exception of clozapine) are allowable. Patients must be on their antipsychotic medication for 1 month and stable on dose of antipsychotic and adjunctive medications for 2 weeks prior to study entry.
You may not be if
history of neurological visual or hearing impairment,
active suicidal ideation on the Columbia Suicide Severity Rating Scale (C-SSRS),
current alcohol or drug abuse (\<1 month) or substance dependence (\<4 months). All women of child-bearing potential must have a negative urine pregnancy test at the baseline visit. We require an IQ of ≥85 to ensure that subjects will have a capacity to learn. In our cross-sectional studies, we have observed an IQ≥85 in over 90% of candidates, suggesting that this is not an overly restrictive criterion.
