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COMPLETEDPhase 4NCT02143934

Effect of Liver and Blood-stage Treatment on Subsequent Plasmodium Reinfection and Morbidity

This study specifically seeks to quantify the contribution of relapes to the burden of P. vivax infections and disease by determining on the effect of radical pre-erythrocytic and erythrocytic clearan...

Lead sponsor: Papua New Guinea Institute of Medical Research•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Papua New Guinea Institute of Medical Research

Collaborators

Walter and Eliza Hall Institute of Medical Research
Swiss Tropical & Public Health Institute
Barcelona Centre for International Health Research

Age

5 - 10 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•aged 5-10 years (±3 months)
•permanent residents of the area
•absence of history of hypersensitivity reactions to the drugs

Exclusion Criteria

•chronic illness
•severe malnutrition (weight-for-age nutritional Z score \[WAZ\] \<60th percentile)
•severe anemia (Hb \<5 g/dL),
•G-6-PD deficiency (\<60% G-6-PD activity)
•permanent disability, which prevents or impedes study participation. Any 1 or more of the criteria is sufficient to exclude study participation.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 21, 2014Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE4

Enrollment524

Start dateAug 2009

Last updatedMay 21, 2014

Condition

Plasmodium Vivax Infection Plasmodium Vivax Clinical Episode Plasmodium Falciparum Infection Plasmodium Falciparum Clinical Episode

Locations shown

PNG Institute of Medical Research

Maprik, East Sepik Province

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 21, 2014Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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