Budesonide for Induction of Remission in Incomplete Microscopic Colitis

Exclusion Criteria

• •Other significant abnormalities in colonoscopy
• •Infectious cause of diarrhoea
• •Clinical suspicion of drug-induced diarrhoea
• •Prior and present MC
• •History of bowel resection
• •Radiation therapy of the abdominal or pelvic region
• •Positive antibody titres for celiac disease
• •Untreated active thyroid dysfunction
• •Any severe concomitant cardiovascular, renal, endocrine, or psychiatric disorder reducing life expectancy
• •Abnormal hepatic function
• •Tuberculosis, hypertension, diabetes mellitus, osteoporosis, peptic ulcer disease, glaucoma, cataract, or infection if careful medical monitoring is not ensured
• •History of colorectal cancer
• •History of cancer (other than colorectal) in the last 5 years
• •Therapy with immunomodulators/budesonide or other steroids/antibiotics/anti-diarrhoeal drugs
• •Current or intended pregnancy or breast-feeding
• •Doubt about the patient's cooperation, e.g. because of addiction to alcohol or drugs
• •Participation in another clinical trial within the last 30 days, simultaneous participation in another clinical trial, or previous participation in this trial