Systemic Corticosteroids in the Perioperative Management of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

Inclusion Criteria

• •Adult patients (ages 18-80) with a diagnosis of chronic rhinosinusitis without nasal polyps (CRSsNP) that have failed a 6 week trial of maximal medical therapy and have elected to undergo endoscopic sinus surgery will be offered enrollment in this study.
• •Diagnosis of chronic rhinosinusitis (CRS) is based on the European Position on Rhinosinusitis (EPOS) 2012 guidelines.
• •These include a greater than 12 week history of inflammation of the nose or paranasal sinuses characterized by at least 2 symptoms.
• •These symptoms must include at least one of the following:
• •* nasal obstruction
• •* rhinorrhea
• •* postnasal drip.
• •Additional symptoms can include facial pain/pressure or anosmia/hyposmia.
• •These symptoms must be supplemented by either endoscopic signs of disease or characteristic CT changes.
• •The presence or absence of nasal polyps defines the subtype (with polyps: CRSwNP; without polyps: CRSsNP).