Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Minnesota
With
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Age
18–90
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
• An individual must be \>18 years of age
Have diagnosed type 2 diabetic mellitus by one of the following criteria:
o Treated with diet, diet plus oral hypoglycemic agents (for at least one year), or insulin preceded by treatment with oral agents (for at least one year).
If treated with insulin, the onset of diabetes must have occurred after age of 40 and the body mass index must be \>25kg/m2 at the time of diagnosis.
Diagnosed kidney attributed to diabetes by one of the following criteria:3
Macroalbuminuria (ACR \>300mg/g, or)
Microalbuminuria (ACR between 30-300 mg/g) or in the presence of diabetic retinopathy (although is recognized that about 1/3 of type 2 diabetics do not have retinopathy by fundoscopic exam).
An elevated ACR should have been confirmed in the absence of urinary tract infections with 2 additional first-void specimens collected over 3-6 months.
At least 2 of 3 samples should fall within the range of micro or macroalbuminuria.
* An estimated Glomerular filtration rate (GFR) of between 90 ml/min and 30 ml/min measured by (GFR (mL/min/1.73 m2) = 186 x (Scr)-1.154 x (Age)-0.203 x (0.742 if female) x (1.210 if African-American) (conventional units).
* Individuals must be able to provide informed consent
* Perform walking exercise testing on a treadmill
* Be able to participate in a 12-week supervised exercise program.
