Impact of Chemo-induced Menopause on Quality of Life in Women <45 Years Old, Diagnosed With Non-metastatic Breast Cancer

Exclusion Criteria

• •Male patient
• •Metastatic cancer
• •Any T4 tumor (skin invasion, deep grip, inflammatory breast cancer)
• •Patient who underwent surgical castration of ovariectomy or hysterectomy or tubal ligation
• •Patients with endometriosis
• •Pregnant or breastfeeding patients
• •Patients with no effective contraception
• •Patients who have had hormone therapy or chemotherapy
• •Patient who have already taken Gn-RH or LH-RH analogues (chemical castration)
• •Patient whose mother was in menopause early without treatment
• •Presence of comorbidities related to fertility or medical history related to ovarian failure or sterility
• •Significant neurological or psychiatric abnormalities
• •Inability of the patient to complete the questionnaires (the language barrier)
• •Patients deprived of liberty by court or administrative decision
• •Patient with another pathology deemed incompatible with the inclusion of the patient in the protocol
• •Participation in another clinical trial involving the chemical or surgical castration of the patient
• •Patients geographically unstable in the 6 months following inclusion or residing away from the treatment center and thereby making it difficult to monitor