Diagnosed histopathologically confirmed and untreated prostatic adenocarcinoma
The general condition and mental status of patients shall permit observation in accordance with the study protocol
Tumor stage (T, M, N):
T3 stage (as indicated by digital rectal examination or MR imaging or other validated imaging technique) T4 tumors can be included if considered resectable/treatable on MR imaging Significant extra-capsular tumor extension in biopsy (rare but acceptable for inclusion) M0 (no sign of distant metastases) confirmed by bone scan or CT or MRT of axial skeleton (at a maximum of pelvis and lumbar vertebral column) N0 stage, defined in accordance to the RECIST guidelines as no sign of macroscopic retroperitoneal lymph-node metastases \>=1.5 cm (short axis) on CT scan, PET-CT, or MRT or more than one suspected lymph-node metastases Presence Gleason grade pattern 4 or 5
\- Signed Informed consent
You may not be if
Patients with a PSA value of \> 100 ng/mL
Anorectal disease, such as fistulae, Crohn´s disease, and ulcerative colitis
