Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Epilepsy

Inclusion Criteria

• •Patient with focal or multifocal epilepsy with or without secondary generalized seizure inoperable at the time of inclusion
• •Failure of pharmacological therapies (pharmacoresistant epilepsy) for over 4 years (persistent seizures despite at least two anti-epileptic treatments used at the optimal dose for at least 2 years)
• •Failure of vagus nerve stimulation, defined as the persistence of crises considered debilitating after 2 years of VNS's treatment
• •VNS failure in a patient treated with VNS, for less than 2 years. with stop early due to the worsening crisis
• •Intelligence quotient above 55
• •Have the written consent of the legal representative for patients under guardianship and minors
• •Affiliation to the french social security system or equivalent
• •People who signed the consent form
• •Seizure frequency at least 4 crisis / month on average for at least 3 months, about 12 crisis in 3 months objectified by the neurologist during visit pre-inclusion, and confirmed by the neurologist after 3 months of Baseline during the inclusion visit