An Open Trial to Assess the Tolerability of AVANZ® Cupressus Immunotherapy

Exclusion Criteria

• •History of severe asthma exacerbation or emergency room visit or admission for asthma in the previous 12 months.
• •Previous treatment with immunotherapy with Cupressus arizonica pollen extract within the last 5 years (initiation of subcutaneous immunotherapy is acceptable if treatment has been discontinued before reaching maintenance dose; for SLIT 3 months in the last 5 years is accepted).
• •Ongoing treatment with any allergen-specific immunotherapy product.
• •A history of anaphylaxis with cardiorespiratory symptoms (immunotherapy, exercise-induced, food allergy, drugs or an idiopathic reaction).
• •A systemic disease affecting the immune system (e.g. insulin-dependent diabetes, autoimmune disease, immune complex disease, or immune deficiency disease whether acquired or not).