Ministry of Science and Technology of the People´s Republic of China
Colorectal cancer (CRC) affects approximately one million people each year with a five-year survival rate of 62% . Considerable interest has recently been focused on the relationship between the chemoprevention of colorectal polyps/CRA and CRC. Therefore, the use of nutritional compounds which are usually less afflicted with the risk of severe side effects for colorectal adenoma (CRA) prevention and health maintenance is an emerging field.
Age
50–80
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
individuals aged 50-80 years
Patients had undergone complete colonoscopy with no adenoma found
Those who voluntarily sign the consent form after being fully informed and understanding the purpose and procedures of the study, characters of the disease, effect of medications, methods of related examinations, and potential risk/benefits of the study
You may not be if
Patients who are hypersensitive or intolerant to the drugs
Patients who are intolerant to another colonoscopy examination
Pregnant women, woman during breast-feeding period, or women with expect pregnancy
Patients with diabetes mellitus, severe heart or renal disease，or cancer history
Patients with malignant neoplasm, or suspicious colorectal cancer
Patients who are not able to cooperate
Individuals who are involved in designing, planning or performing this experiment
Patients with medical conditions who are not appropriate to participate the study
Patients who are take aspirin or cyclooxygenase 2 inhibitor （COX2）.
Clareo Health | Study of Folic Acid, Calcium and Vitamin D in Preventing Colorectal Polyps and Colorectal Cancer
