Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Akebia Therapeutics
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Healthy, non-smoking males or females, 18 and 55 years of age, inclusive
BMI 18.0 and 32.0 kg/m2, inclusive
non clinically significant 12-lead ECG
heart rate of 45 to 90 beats per minute, inclusive
mean systolic blood pressure \<141 mmHg and mean diastolic blood pressure \< 90 mmHg
You may not be if
history or presence of significant cardiovascular, pulmonary, hepatic, renal, hematologic, GI, endocrine, immunologic, dermatologic, neurologic, or psychiatric disease
history of unexplained syncope, cardiac arrest, unexplained cardiac arrhythmias, or torsades de pointes, structural heart disease, or a family history of Long QT syndrome
significant abnormalities in liver function tests
history of stomach or intestinal surgery or resection that would potentially alter absorption and/or excretion of orally administered drugs
history of Gilbert's Syndrome
positive hepatitis panel
seizure disorder or receiving anti-epilepsy medication for seizure disorder
any acute or chronic condition that, in the opinion of the Investigator, may pose a safety risk to a subject in this study or which would limit the subject's ability to complete and/or participate in this clinical study
