ADA Linagliptin in Long Term Care

Exclusion Criteria

• •1. Subjects with a history of type 1 diabetes or with a history of diabetic ketoacidosis
• •2. Treatment with insulin or GLP1 analogs during the past 3 months prior to admission.
• •3. Recurrent severe hypoglycemia or hypoglycemic unawareness.
• •4. Subjects with history of gastrointestinal obstruction or gastroparesis.
• •5. Patients with acute or chronic pancreatitis or pancreatic cancer.
• •6. Patients with clinically significant hepatic disease (cirrhosis, jaundice, end-stage liver disease, portal hypertension) and elevated ALT and AST \> 3 times upper limit of normal, or significantly impaired renal function (GFR \< 45 ml/min).
• •7. Treatment with corticosteroids, parenteral nutrition and immunosuppressive treatment.
• •8. Mental condition rendering the subject unable to understand the nature and scope of the study.