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TERMINATEDNANCT02058810

Nasal High Flow at Acute Hart Failure

The pilot study aims to compare the results of using a new respirator (OPTIFLOW TM-High-Flow-Machine) with those from Standard-Oxygen-Therapy during the stabilization of patients who have been hospita...

Lead sponsor: University Hospital Regensburg•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University Hospital Regensburg

Collaborators

University of Magdeburg

Primary endpoint: Improvement of the cardiorenal syndrome type1 measured by the improvement of creatine clearance and the Serum-Creatinin of patients undergoing High-Flow treatment. Secondary endpoints: Worsening of cardiac insufficiency (application of catecholamines, need of NIV, intubation, death) Duration of hospital stay (in days) 90-day mortality Readmittance to hospital within 3 months Intrathoracic bloodvolume at hospital discharge Change of dyspnea at 3h, 6h, 24h \> VAS-0-100 (visual analog scale) Change in the diameter of the IVC (inferior vena cava) as a non-invasive parameter for assessing the degree of decompensation Change in the BNP (hospital admission vs. discharge, after 3 months) Weight loss in hospital Amount of diuretics

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•patients with acute heartfailure NYHA III und IV

Exclusion Criteria

•Patients wit respiratory insufficency and indication for mechanical ventilation
•Asthma bronchiale
•severe COPD
•cardiogenic shock (RR persisting\< 90mmHg systolic or catecholamine application)
•renal dialysis

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 26, 2019Terms

Trial snapshot

StatusTERMINATED

PhaseNA

Enrollment46

Start dateSep 2010

Last updatedSep 26, 2019

Condition

Decompensated Heartfailure Cardio-renal Syndrom

Locations shown

UHMagdeburg

Magdeburg, Saxony-Anhalt

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 26, 2019Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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