Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Steven Burton
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Male or female patients ≥ 18 years of age
A life expectancy of at least 12 weeks with a Karnofsky performance status of at least 70 (Appendix II)
The target lesion(s) can be accurately measured in at least one dimension according to RECIST
No prior radiotherapy to the brain
Previous or concurrent systemic or targeted chemotherapy is allowed
Patients must have an extra-cranial primary tumor diagnosis
Patients will have no more than 3 distinct lesions within the brain. At least 1 lesion must be a minimum of 3cm in greatest dimension, no larger than 5cm which will be treatable by fractionated stereotactic radiosurgery
The additional lesions will each be treated with single fraction stereotactic radiosurgery
Patient may be on steroids or anti-epileptics
Must be aware of the neoplastic nature of his/her disease and willingly provide written, informed consent after being informed of the procedure to be followed, the experimental nature of the therapy, alternatives, potential benefits, side-effects, risks and discomforts
Patients do not need a histologically proven diagnosis of brain mets
You may not be if
Symptomatic patients in need of surgery to the "target" lesion
Four or more newly-diagnosed lesions
Prior surgical resection of targeted tumor
Prior WBRT
Primary brain tumor
Pregnant or breast-feeding patients
Primary tumor histology of lymphoma, leukemia, multiple myeloma or germ cell tumor
Clareo Health | Fractionated Stereotactic Radiosurgery for Large Brain Metastases
