Safety, Tolerability and Immunogenicity of V114 in Healthy Adults and Infants (V114-004)

Exclusion Criteria

• •Infants and Adults:
• •Prior administration of any pneumococcal vaccine, any non-live vaccine within 14 days, or any live vaccine within 30 days.
• •History of invasive pneumococcal disease.
• •Known hypersensitivity to any vaccine component.
• •Received systemic corticosteroids within 14 days of first vaccination.
• •Known or suspected impairment of immune function.
• •Febrile illness within 72 hours before vaccination.
• •Received blood transfusion or blood products within 30 days. Infants
• •Mother has documented human immunodeficiency virus or is hepatitis B surface antigen positive.
• •Has asplenia or failure to thrive.
• •Adults:
• •\- Is breastfeeding.