Clinical Implications of Genetic Variations of Venous Stasis Ulceration

Exclusion Criteria

• •\<18 y.o.
• •inability to comply w/compression therapy
• •Inability to maintain f/u schedule
• •ABI (ankle-brachial index) \< 0.5 if pedal pulses are not palpable
• •Inability to ambulate w/active ulcer (N/A for Group 2)
• •Diabetic w/ABI \<0.5
• •Severe premorbid systemic disease such as pulmonary failure, heart failure, renal failure, or hepatic failure w/a life expectancy of \<1 year
• •Chronic steroid therapy Group 3-Controls
• •\<50y.o.
• •ABI (ankle-brachial index) \< 0.5 if pedal pulses are not palpable
• •Diabetic w/ABI \< 0.5
• •Severe premorbid systemic disease such as pulmonary failure, heart failure, renal failure, or hepatic failure w/a life expectancy of \<1 year
• •Chronic steroid therapy