Inclusion criteria:
1. Men who are being referred as new urological outpatient and meet the following criteria:
1. Wanted clinical examined because of elevated PSA
2. Not strong family history of prostate cancer
3. It is taken biopsy as part of routine investigation.
2. Control groups: Men being referred to urological / gastroenterological outpatient clinic, and which meet the following criteria:
1. urination complaints, normal PSA, and study shows prostate size\> 40cc
2. Or melena and cancer suspicion in colorectum
3. Age\> 18 years and \<75 years
Outcome measures:
Together with statistician look for patterns / covariance in replies from those who are diagnosed with prostate cancer in the questionnaires personality evaluation adapted to normal population (Neo-FFI), gender differentiated stress response questionnaire (MGRSS) and questionnaires related to resilience, relationship and quality of life index, compared with the control groups.
