A Dose-Ranging Study of the Effect of Glycopyrrolate in Subjects With Axillary Hyperhidrosis

Exclusion Criteria

• •Prior surgical procedure for hyperhidrosis.
• •Any prior treatment with an axillary anti-hyperhidrosis medical device (approved or investigational)
• •Prior treatment with botulinum toxin for axillary hyperhidrosis within 1 year.
• •Treatment with cholinergic, serotonergic antagonists, and dopamine partial agonists thought to relieve antidepressant-induced hyperhidrosis. Treatment with psychotherapeutic medications for less than 4 months prior to study enrollment. - Treatment with topical or systemic anticholinergics, adrenergic agonists (clonidine), or beta-blockers within 4 weeks prior to enrollment.
• •Prior axillary treatment with axillary iontophoresis within 4 weeks.
• •Axillary use of nonprescription or prescription antiperspirants within 2 weeks of study enrollment.
• •Known history of a condition that may cause secondary hyperhidrosis.
• •Known history of Sjögren's syndrome or Sicca syndrome.
• •Abnormal findings on screening ECG deemed clinically significant by the Investigator.