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Non Ablative Fractional Laser Treatment of Burn Scars | Clinical Trials | Clareo Health

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Non Ablative Fractional Laser Treatment of Burn Scars

LONG-TERM AND CONTINUED IMPROVEMENT OF MATURE BURN SCARS IN RESPONSE TO NONABLATIVE FRACTIONAL LASER - A RANDOMIZED CONTROLLED TRIAL WITH HISTOLOGICAL EVALUATION

NCT02014298•Bispebjerg Hospital

View on ClinicalTrials.gov

Summary

BACKGROUND: Increasing evidence appears for non-ablative fractional laser (NAFL) to remodel mature burn scars. OBJECTIVES: To investigate long-term clinical and histological appearance of mature burn scars after NAFL-treatment. HYPOTHESIS: That NAFL can modulate mature burn scars with subsequently improved cosmetic and functional appearance. METHODS: Study patients with burn scars at trunk or extremities. Side-by-side test areas are randomized to three monthly 1,540 nm NAFL-treatments or control, followed by blinded evaluations at 1, 3, and 6 months using mPOSAS (modified Patient and Observer Scar Assessment Scale; 1 = normal skin, 10 = worst imaginable scar).

Eligibility

Age

18 - 60 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•legally competent adults aged 18-60 years
•Fitzpatrick skin type I-III
•burn scar 1 year or older
•total scar area allowing selection of two similar side-by-side test areas of minimum 1.5 × 3 cm for study purpose

Exclusion Criteria

•pregnancy or lactation
•suntan
•wounds or infections in study area
•tendency to form hypertrophic scars or keloids
•oral retinoids, anti-inflammatory or immunosuppressive drugs within the last six months
•current anticoagulants
•previous treatments in test area with laser, Intense Pulsed Light, dermabrasion, chemical peel or filler.

Locations (1)

Bispebjerg Hospital, University of Copenhagen

Copenhagen NV, Copenhagen, Denmark

Key Dates

Start Date

January 1, 2012

Primary Completion Date

October 1, 2012

Completion Date

October 1, 2012

Last Updated

December 18, 2013

Enrollment

ACTUAL participants

Conditions

Burn Scars

Interventions

non-ablative fractional laser

RADIATION

control

OTHER

Pilot Safety and Efficacy Study of Isolagen Therapy in Treatment of Restrictive Burn Scars

NCT00620737

Restrictive Burn Scars of Joint Area

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 18, 2013Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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