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Adjunctive Aripiprazole in the Treatment of Risperidone-Induced Hyperprolactinemia: A Randomized, Double-Blind, Placebo-Controlled, Dose-Response Study
Hyperprolactinemia is a frequent consequence of treatment with typical antipsychotic agents and atypical antipsychotics such as risperidone. Recent studies have suggested that aripiprazole, a partial dopamine agonist, reduces the prolactin response to antipsychotics. Thus, we conducted this study to evaluate the dose effects of adjunctive treatment with aripiprazole on hyperprolactinemia in stable schizophrenic patients maintained with risperidone.
Age
18 - 45 years
Sex
ALL
Healthy Volunteers
No
Beijing HuiLongGuan Hospital
Beijing, Beijing Municipality, China
Start Date
February 1, 2013
Primary Completion Date
January 1, 2014
Completion Date
February 1, 2014
Last Updated
December 17, 2013
120
ESTIMATED participants
Aripiprazole
DRUG
Lead Sponsor
Beijing HuiLongGuan Hospital
NCT07455929
NCT06740383
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