Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Affiris AG
Age
50–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
patients having participated in AFF006+having received 6 investigational medicinal product (IMP) injections+having completed all visits
Written informed consent
Availability of a partner/caregiver
Scheduled elective hospitalization for diagnostic work-up is allowed for inclusion into the clinical trial.
You may not be if
Pregnant women.
Sexually active women of childbearing potential who are not using a medically accepted birth control method and unreliable contraception in male subjects.
Participation in the active treatment phase of another clinical trial except AFF006 within 3 months before Visit 0.
History of questionable compliance to visit schedule; patients not expected to complete the clinical trial.
Presence or history of allergy to components of the vaccine, if considered relevant by the investigator.
Contraindication for MRI imaging
Presence and/or history of immunodeficiency (e.g., HIV infection).
Prior and/or current treatment with experimental immunotherapeutics including Intravenous immunoglobulin (IVIG), AD antibody therapy and/or vaccines for AD except AD02.
Prior and/or current treatment with immunosuppressive drugs.
Treatment with benzodiazepines and/or nootropics administered at high doses and/or as newly started treatment.
Treatment with anticholinergic drugs including Parkinson treatments, antidepressants (tricyclics), neuroleptics with anticholinergic properties, certain bladder relaxants, anticholinergic drugs for use in lung diseases.
