Finding studies
Finding studies
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Lead
Andrew Sikora
With
This is an investigator-initiated prospective clinical study of patients with stage I-IV squamous cell carcinoma of the oropharynx (OPSCC) who are to undergo ablative transoral robotic surgery (TORS). There is a vaccination group and a control group in this study. Subjects in the control group will not receive the vaccination and will only be followed after TORS surgery for additional research blood tests to measure how their immune system is working. Subjects in the vaccination group will receive two vaccinations prior to surgery. The first dose will be about 33 days before surgery, and the second will be about 14 days before surgery. Participation in this study will also include allowing the research team to take several blood samples from the subject at various times before, during, and after treatment for his/her cancer. Vaccination subjects will be monitored closely after treatment and includes 6 months of oral antibiotics.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted