Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Pennsylvania
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Female subjects 18 years of age and older
2. Female subjects of childbearing potential or less than 2 years postmenopausal agree to receive a urinary or serum beta HCG test prior to subject enrollment. Documentation must be acquired for women of menopausal or post-menopausal status prior to subject enrollment if they are below the age of sixty (60).
3. Primary diagnosis, or at high clinical suspicion, of primary ovarian cancer:
1. Patient is scheduled to undergo laparotomy OR
2. Patient is scheduled to undergo laparoscopy then pre-authorized laparotomy if cancer is found.
You may not be if
1\. Known sarcomatous histologies
1. Recurrent ovarian cancer
2. Known FR-alpha negative cancer
3. Planned surgical approach via laparoscopy or robotic (no intention to perform laparotomy)
4. History of anaphylactic reactions to Folate-FITC (EC17) or insects
5. Pregnancy
6. Brain metastases
7. Taking compounds that inhibit active transport of organic anions (probenecid)
8. Hepatic impairment, as evidenced by greater than 3x the upper limit of normal (ULN) for ALT, AST, or total bilirubin (except for known cases of Gilbert's syndrome), or renal impairment, as evidenced by greater than 1.5x the ULN for BUN or creatinine
9. Received study agent in another investigational drug or vaccine trial prior to surgery
10. At-risk patient populations
1. People who would easily be lost to follow up (ex: People who are homeless or alcohol dependent)
2. Patients unable to participate in the consent process (children and neonates)
