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Response to NonInvasive Mechanical Ventilation According to the Breathing Pattern | Clinical Trials | Clareo Health

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Response to NonInvasive Mechanical Ventilation According to the Breathing Pattern

NCT01991535•Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Summary

The purpose of this study is to determine whether breathing pattern (specifically the inspiratory time/total respiratory cycle value) has an influence over the response to the noninvasive mechanical ventilation.

Detailed Description

Breathing pattern will be analyzed along the adaptation to 3 different NonInvasive-Mechanical-Ventilation modes (controlled mode, spontaneous mode and placebo mode or simulator).

Eligibility

Age

18 - 90 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Hypercapnic chronic respiratory failure due to restrictive pulmonary disease (with usual criteria for home NonInvasive Mechanical Ventilation).
•Transcutaneous carbon dioxide (CO2) basal pressure ≥ 50 mmHg when conscious.
•Clinically stable (within the previous month).
•Patients without previous NonInvasive Mechanical Ventilation treatment.

Exclusion Criteria

•Clinical exacerbation.
•Chronic airflow limitation Forced expiratory volume in 1 second/Forced vital capacity (FEV1/FVC) ratio \< 70% or Sleep Apnea-Hypopnea Syndrome

Locations (1)

Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Barcelona, Spain

Key Dates

Primary Completion Date

December 1, 2016

Last Updated

March 21, 2024

Conditions

Neuromuscular DisordersChest Wall DisordersObesity Hypoventilation Syndrome (OHS)

Interventions

Spontaneous Ventilation Mode

DEVICE

Controlled Ventilation Mode

DEVICE

Simulator Ventilation Mode

DEVICE

Bidirectional Tuning of the AFO Stiffness

NCT06412055

Neuromuscular Disorders

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COMPLETED

Relation Between Muscle Architecture and Functional Ability in Children With Duchenne Muscular Dystrophy

NCT07437378

Duchenne Muscular Dystrophy (DMD)Neuromuscular Disorders+1 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 21, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Response to NonInvasive Mechanical Ventilation According to the Breathing Pattern

Inclusion Criteria

Exclusion Criteria

Bidirectional Tuning of the AFO Stiffness

Relation Between Muscle Architecture and Functional Ability in Children With Duchenne Muscular Dystrophy

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