Sancuso® for Gastroparesis: An Open Label Study.

Objectives The aim of this study is determine the efficacy of Sancuso® in improving symptoms of nausea and vomiting in patients with gastroparesis. The specific objectives of this study are to determine: 1. Determine the treatment response of Sancuso® in gastroparetic patients with nausea and/or vomiting. 2. Determine which specific symptoms of gastroparesis improve - nausea, vomiting, early satiety, abdominal distension, abdominal pain 3. To determine symptomatic responses in both diabetic and idiopathic gastroparesis 4. To determine the time course of symptom improvement (with Sancuso® for symptoms of gastroparesis; The hypotheses to be tested include: 1. Sancuso® improves symptoms of gastroparesis. 2. Symptoms of nausea and vomiting improve to a greater degree than abdominal pain. 3. The beneficial response of Sancuso® is seen in both diabetic and idiopathic gastroparesis. 4. The symptom reduction occurs on days 3 after starting treatment and continues throughout the treatment course.