Lead Sponsor

University of Michigan Rogel Cancer Center

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Patients receiving partial brain irradiation for malignant or benign brain tumors (including low-grade gliomas, high-grade gliomas, malignant meningioma, pituitary adenomas, supratentorial meningioma, or craniopharyngiomas); or patients receiving whole brain irradiation for brain metastases.
•Patients must be 18 years of age or older
•Patients must sign a study specific consent form approved by the Institutional Review Board (IRB) of the University of Michigan prior to study entry.
•Patients must have a neurological function class 1 or 2 with a Karnofsky performance status (a scoring system used to quantify general well being and quality of life on a scale of 100 to 0) of greater than or equal to 70.
•Patients must have an expected life expectancy of greater than 6 months.

•Patients with a history of major medical illness or psychiatric impairment which, in the investigator's opinion, will prevent administration of the protocol.
•Patients who have had prior external beam irradiation to the brain or head/neck area that will lead to overlap of the radiation field.
•Patients should have no contraindications to having a contrast enhanced Magnetic Resonance Imaging (MRI) scan.
•Prisoners are excluded.
•Pregnant women are excluded.