Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Calgary
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients must be 18-65 years of age.
Be naive to Upper Cervical Chiropractic care. Other forms of chiropractic care in the past are permitted.
Have migraine with or without aura.
Have between 10-26 headache days per month over the last 4 months.
Have at least 4 separate headache episodes per month, with episodes separated by at least 4 hours of painfree time.
Have at least 8 days per month with pain of levels greater than or equal to 4/10 for part of the day, or have attacks successfully treated with migraine specific medication.
Be candidates suitable for NUCCA therapeutic intervention because of atlas displacement as assessed by NUCCA investigator.
Subjects on acceptable pharmacological prophylaxis must either remain on a stable dose throughout the study, or stop the prophylactic medication one month before entering the baseline period.
You may not be if
Any medical or psychiatric condition which in the opinion of the investigator would make the subject unsuitable for enrolment, because of inability to comply with study requirements or possible confounding of the results.
Headache on more than 26 days per month.
Acute medication overuse as defined by the International Classification of Headache Disorders.
Pregnancy or lactation
Severe cervical spine degeneration as assessed by cervical spine x-ray.
Claustrophobia or any condition that contraindicates an MRI scan
A history of cardiovascular disease, cerebrovascular disease, brain surgery, or other central nervous system disorder.
Other chronic pain disorder which might interfere with headache assessment or study procedures.
A history of significant hypo- or hypertension as determined by the investigator.
Subject on a beta-blocker, calcium channel blocker, or other medication which the investigator considers might alter cerebral vascular regulation. Triptans are allowed, but must not be taken within 24 hours (48 hours for frovatriptan) before an MRI study.
A history of substance abuse or dependence within 1 year.
Current participation in a research study or within the last 30 days.
Any spinal chiropractic care outside of the study protocol is prohibited during the baseline and treatment period.
Use of botulinum A within 4 months of study entry.
A history of significant head or neck trauma (as judged by the investigator) within the year prior to study entry.
