Bolus of Saline in Stroke

Exclusion Criteria

• •Infarct limited to the brainstem and/or cerebellum with no involvement of the cerebral hemispheres
• •Bi-hemispheric infarction or acute infarct in the contra-lateral hemisphere within the past 30 days
• •Symptoms of active congestive heart failure (dyspnea, orthopnea, increased oxygen requirement)
• •Exacerbation of congestive heart failure, requiring hospitalization, within the past 30 days or severe systolic dysfunction with a known ejection fraction \<20%
• •End stage renal disease requiring hemodialysis or a creatinine clearance \<20 ml/min/1.73 m2
• •Hemicraniectomy or other skull defect that would interfere with monitoring
• •Pregnant women are excluded. Women of child-bearing age must have a negative pregnancy test prior to enrollment
• •Participation in another clinical trial
• •Any other illness or condition that the investigator feels would pose a hazard to the subject from participation in the study