Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Massachusetts General Hospital
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age \>18
With clinical diagnosis of herpes labialis.
who self report having six or more episodes of herpes labialis in the previous 12 months.
You may not be if
Pregnant or lactating females.
Current or recurrent infection or any underlying condition that may predispose to infection or anyone who has been admitted to the hospital due to bacteremia, pneumonia or any other serious infection.
Therapy with glucocorticoid or immunosuppressant at time of recruitment or within past 4 weeks, except for inhaled corticosteroids for asthma.
History of malignancy (except patients with surgically cured basal cell or squamous cell skin cancers who will be eligible)
History of organ transplantation
Negative HIV-positive status determined by history at screening or known history of any other immuno-suppressing disease.
Severe comorbidities (diabetes mellitus requiring insulin, CHF (EF\<50% at baseline will be exclusionary) of any severity, MI, CVA or TIA within 3 months of screening visit, unstable angina pectoris, oxygen-dependent severe pulmonary disease
Subject is currently enrolled in another investigational device or drug trial(s), or subject has received other investigational agent(s) within 28 days of baseline visit.
Subjects who have known hypersensitivity to Squaric acid or any of its components.
History of recent alcohol or substance abuse (\< 1 year)
Any condition judged by the investigator to cause this clinical trial to be detrimental to the patient.
History of psychiatric disease that would interfere with the patient's ability to comply with the study protocol
