Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Kyowa Kirin Co., Ltd.
With
Kyowa Hakko Kirin Pharma, Inc.
Age
30–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
30 years of age or older.
UK Parkinson's Disease Society (UKPDS) brain bank criteria (Step 1 and 2) for PD
PD Stages 2-4 in the ON state for Modified Hoehn and Yahr Scale.
On levodopa therapy for at least 1 year with beneficial clinical response at the baseline visit
Taking at least 400mg levodopa combination daily and on stable regimen of any other anti-Parkinsonian drugs (MAO-B, COMT, DA) for at least 2 weeks prior to randomization
Stable dopaminergic regimen for at least 4 weeks immediately prior to randomization
Documented end-of-dose wearing-off and levodopa-induced dyskinesia
Have an average of two hours of OFF time per day
You may not be if
Subjects on apomorphine and/or dopamine receptor antagonists or direct gastrointestinal levodopa infusion.
Subject who have had neurosurgical operation for PD
