Examination of Whether Host Preconditioning Modifies Short-term Transplant Survival

Exclusion Criteria

• •Use of any topical AD treatments (including topical steroids, topical calcineurin inhibitors) to either arm within one week of either screening visit
• •Use of any oral/systemic AD therapies (antihistamines, steroids) within 28 days of either screening visit
• •Subjects who have taken a bleach bath within a week prior to screening, or who take bleach baths during the study
• •Patients with severe medical condition(s) that in the view of the investigator prohibits participation in the study
• •Subjects with Netherton's syndrome or other genodermatoses that result in a defective epidermal barrier
• •Any subject who is immunocompromised (e.g. provides researchers with a history lymphoma, HIV/AIDS, Wiskott-Aldrich Syndrome) or has a history of malignant disease (with the exception of non-melanomatous skin cancer). This information will be gathered verbally from the patient while taking a medical history from the patient, and will not involve further testing such as an HIV test.
• •Subjects with a history of psychiatric disease or history of alcohol or drug abuse that would interfere with the ability to comply with the study protocol
• •Active bacterial, viral or fungal skin infections
• •Any noticeable breaks or cracks in the skin on either arm, including severely excoriated skin or skin with open or weeping wounds suggestive of an active infection or increased susceptibility to infection.
• •Ongoing participation in another investigational trial
• •Use of any oral or topical antibiotic for up to four weeks prior to screening
• •Use of any systemic immunosuppressive therapy (e.g. cyclosporine, methotrexate, etc.) within four weeks of screening.
• •Sensitivity to or difficulty tolerating Dove fragrance-free bar soap, Dial antibacterial liquid soap, Cetaphil lotion, or alcohol-based cleaners