The Follow-up Study of Chronic Hepatitis B Patients With Liver Cirrhosis Receiving Anti-HBV Therapy

Inclusion Criteria

• •1. Age older than 20 years old.
• •2. HBsAg (+) \> 6 months
• •3. Baseline serum HBV DNA ≧ 2000 IU/mL (10,000 copies/mL)
• •4. Liver cirrhosis (Child A) before or at enrollment, diagnosed by 1). Liver biopsy（Metavir F4 or Ishak \> F5） or 2). Ultrasonographic evidence of cirrhosis with signs of portal hypertension (splenomegaly or presence of esophageal or gastric varices)
• •5. Receiving long-term anti-HBV therapy
• •1. Age older than 20 years old.
• •2. HBsAg (+) \> 6 months
• •3. Baseline serum HBV DNA ≧ 2000 IU/mL (10,000 copies/mL)
• •4. Liver cirrhosis (Child A) before or at enrollment, diagnosed by 1). Liver biopsy（Metavir F4 or Ishak \> F5） or 2). Ultrasonographic evidence of cirrhosis with signs of portal hypertension (splenomegaly or presence of esophageal or gastric varices)
• •5. without receiving treatment