Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Utah
Age
13–21
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Inclusion of Major Depressive Disorder Participants:
1. Male and female patients between the ages of 13 and 17 years
2. Participants must be able to give informed assent, and parent(s)/guardian(s) must be able to give informed permission for study participation
3. Diagnosis of MDD or depression not otherwise specified, as defined by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition-TR criteria (DSM-IV-TR)
4. Current mood state depressed for \> 2 weeks
Inclusion of Bipolar Disorder Participants:
1. Male and female patients between the ages of 13 and 17 years
2. Participants must be able to give informed assent, and parent (s)/guardian (s) must be able to give informed permission for study participation
3. Diagnosis of Bipolar I Disorder, Bipolar II Disorder, or not otherwise specified, as defined by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition-TR criteria
4. Current mood state depressed for \> 2 weeks
Inclusion of Healthy Control Participants:
1. Males and females between the ages of 13 and 17 years
2. Participants must not meet DSM-IV-TR diagnostic criteria for a psychiatric or substance abuse disorder
3. Participants must be able to give informed assent and parent (s)/guardian (s) must be able to give informed permission for study participation
You may not be if
Exclusion of Major Depressive Disorder and Bipolar Disorder Participants:
1. Meet the DSM-IV criteria for substance abuse or dependence in the last month
2. History of fainting or other significant adverse event during blood draws in the past
3. Dysthymia
4. Daily use of oral or inhaled steroids
5. High risk of suicidal behaviors, homicidal behaviors, or self-harm
6. A medical condition, such as Addison's Disease, which is highly likely to influence the inflammatory or HPA responses
Exclusion of Healthy Control Participants:
1. Clinically significant psychiatric or substance abuse disorder
2. Unstable medical or neurological illness
3. History of fainting or other significant adverse event during blood draws in the past
4. Daily use of oral or inhaled steroids
5. A medical condition, such as Addison's Disease, which is highly likely to influence the inflammatory or HPA responses
Clareo Health | Detecting Depression and Bipolar Disorder in Adolescents Using a Biomarker Panel
