Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Institut Curie
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
To be eligible to participate in the study, patients must fulfill all of the following criteria:
Female patients. Age ≥ 18 years. ECOG performance status ≤ 2. Metastatic breast carcinoma, either at diagnosis or at first metastatic relapse.
Available FFPE +/- frozen primary tumor samples. Evaluable metastatic disease. Metastatic disease outside any previous radiotherapy field (e.g. sub-clavicular or internal mammary lymph nodes).
Metastatic disease accessible to either percutaneous or surgical sampling. Signed written informed consent (approved by an Independent Ethics Committee and obtained prior to any study-specific screening procedure).
Social and psychological welfare in concordance with compliance to the study.
You may not be if
To be eligible to participate in the study, patients must fulfill none of the following criteria:
Bilateral or multifocal breast cancer. Isolated local or contralateral relapse.
Solitary bone and/or brain metastatic disease unless :
Metastatic sites eligible for a therapeutic surgery. Metastatic sites sampled for diagnosis purpose. Past or current history of malignant neoplasms, except for curatively treated basal and squamous cell carcinoma of the skin. Carcinoma in situ of the cervix. Any coagulopathy contraindicating tumor biopsy. Presence of a contraindication to general anesthesia, if required.
