The Effects Of HMO On The Faecal Microbiota And On Gastrointestinal Symptoms In Healthy Volunteers

Exclusion Criteria

• •Participation in a clinical study one month prior to screening visit and throughout the study.
• •Abnormal results of the screening laboratory tests clinically relevant for study participation, as judged by the investigator.
• •Any gastrointestinal symptom scored \>3 on the GSRS during the screening period
• •A mean score on the total GSRS \>2 (i.e. above the population norm value) during the screening period
• •Any gastrointestinal disease(s) that may cause symptoms or may interfere with the trial outcome, as judged by the investigator.
• •Other severe disease(s) such as malignancy, diabetes, severe coronary disease, kidney disease or neurological disease, as judged by the investigator.
• •Severe psychiatric disease, as judged by the investigator.
• •Use of highly dosed probiotic supplements (yoghurt allowed) 3 months prior to the study and throughout the study.
• •Consumption of antibiotic drugs 3 months prior to screening and throughout the study.
• •Consumption on a regular basis of medication that might interfere with symptom evaluation (as judged by the investigator) 2 weeks prior to screening and throughout the study.
• •Pregnant or lactating or wish to become pregnant during the period of the study.
• •Lack of suitability for participation in the study for any reason as judged by the investigator.