Effects of REnal Denervation for Resistant Hypertension on Exercise Diastolic Function and Regression of Atherosclerosis and the Evaluation of NEW Methods Predicting A successfuL Renal Sympathetic Denervation (RENEWAL-EXERCISE, -REGRESS, and -PREDICT Trial From RENEWAL RDN Registry)
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Yonsei University
Age
20–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients aged 20-85 years with resistant hypertension defined as systolic BP\>140 mmHg (\>130 mmHg for diabetes) or diastolic BP\>90mmHg (\>80 mmHg for diabetes) despite adequate administration of 3 or more different classes of anti-hypertensive medications including diuretics with good adherence and adequate treatment regimen.
All agents should be prescribed at optimal dose amounts. BP was based on an average of 3 office BP readings measured according to the general guidelines. Patients are adhering to a stable drug regimen including 3 or more antihypertensive medications (with no changes for a minimum of 2 weeks prior to enrollment).
Patients provided with the written, informed consent to participate in this study
You may not be if
Hemodynamically or anatomically significant renal artery abnormalities, main renal arteries \< 4 mm in diameter or \< 20 mm in length, or.prior renal artery intervention
Estimated glomerular filtration rate (eGFR) of \< 30mL/min/1.73m2, using the MDRD calculation
History of congestive heart failure with reduce LV ejection fraction of less than 35%
CVA in the prior 3 months
ST-segment elevation MI within 48 hours
Scheduled or planned surgery or cardiovascular intervention in the next 6 months.
Patients with chronic debilitating disease with life expectancy of less than 1 year
Patients taking hormone replace treatment and/or oral contraceptives; pregnant, nursing or planning to be pregnant
Chronic liver cirrhosis
Clareo Health | Effects of REnal Denervation for Resistant Hypertension on Exercise Diastolic Function and Regression of Atherosclerosis and the Evaluation of NEW Methods Predicting A successfuL Renal Sympathetic Denervation (RENEWAL-EXERCISE, -REGRESS, and -PREDICT Trial From RENEWAL RDN Registry)
