1. Histologically confirmed adenocarcinoma of the prostate

2. Age range of 50-80

3. ECOG performance status 0-1

4. Life expectancy \> 5 years

5. Must be enrolled in a social security program

6. No other cancer, except basal cell skin cancer, that has been treated or relapsed within the past 5 years

7. No severe uncontrolled hypertension (systolic BP ≥ 160 mm Hg or diastolic BP ≥ 90 mm Hg)

8. No contraindication to luteinizing hormone-releasing hormone agonists

9. No contraindication to pelvic irradiation (e.g., scleroderma, chronic inflammatory gastrointestinal disease)

10. No hip prosthesis

11. Must not be deprived of liberty or under guardianship

12. No geographical, social, or psychological reasons that would preclude follow up

Radiosensitizing and Radioprotectve Effects of Curcumin in Prostate Cancer